ZLN005
ZLN005 是新型过氧化物增殖激活受体协同激活子 (PGC-1α) 激活剂。
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| Free Sample (0.1-0.5 mg) | Apply now | ||
| 10 mM * 1 mL in DMSO | ￥605 | In-stock | |
| 10 mg | ￥550 | In-stock | |
| 50 mg | ￥2000 | In-stock |
| 生物活性 | ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1]. | ||||||||||||||||
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| IC50 & Target | Peroxisome proliferator-activated receptor-γ coactivator-1α[1] | ||||||||||||||||
| 体外研究 (In Vitro) | ZLN005 (2.5-20 μM; 24 hours ) activates AMPK in a dose-dependent manner[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
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| 体内研究 (In Vivo) | ZLN005 (15 mg/kg; p.o.; per day for 4 weeks) decreases random blood glucose and fasting blood glucose levels over 4 weeks compared with lean mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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| 分子量 | 250.34 | ||||||||||||||||
| Formula | C₁₇H₁₈N₂ | ||||||||||||||||
| CAS 号 | |||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
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| 溶解性数据 | In Vitro: DMSO : 22 mg/mL (87.88 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂： ——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。 | ||||||||||||||||
| 参考文献 |
